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NBD-Pen

CAT: 0804-HY-129109-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-129109-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NBD-Pen is the first fluorescence probe for lipid radicals with high selectivity and sensitivity (λex: 470 nm, λem: 530 nm) . NBD-Pen specifically detects lipid derived radicals over other reactive species present in biological systems, including H2O2, ClO-, O2-∙, and ∙OH. NBD-Pen directly detects lipid radicals in living cells by turn-on fluorescence. NBD-Pen decreases inflammation, apoptosis, and oxidative stress markers. NBD-Pen can be studied in various disease models such as hepatic carcinoma[1].
CAS Number
1955505-54-0
UNSPSC
12171500
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/nbd-pen.html
Purity
99.94
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
[O]N1C(C)(C)CC(NC2=CC=C([N+]([O-])=O)C3=NON=C32)CC1(C)CCCCC
Molecular Formula
C19H28N5O4?
Molecular Weight
390.46
References & Citations
[1]Ishida Y, et al. Detection and inhibition of lipid-derived radicals in low-density lipoprotein. Free Radic Biol Med. 2017 Dec;113:487-493.|[2]Yamada, K., et al., (2016) . Fluorescence probes to detect lipid-derived radicals. Nature chemical biology, 12 (8), 608–613.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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