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20-Hydroxy-PGF2α

CAT: 0804-HY-137547-01Size: 50 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-137547-01Size:50 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
20-hydroxy Prostaglandin F2α (20-hydroxy PGF2α) is the ω-oxidation product of PGF2α. Cultured type II alveolar cells from pregnant rabbits metabolize exogenous PGF2α via microsomal cytochrome P450 ω-oxidation, producing 20-hydroxy PGF2α and its 15-hydroxy PGDH metabolites. Cells from male rabbits exhibit only the 15-hydroxy PGDH pathway.
CAS Number
57930-92-4
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/20-hydroxy-pgf2α.html
Smiles
OC(CCC/C=C\C[C@@H]([C@H](C1)O)[C@H]([C@@H]1O)/C=C/[C@@H](O)CCCCCO)=O
Molecular Formula
C20H34O6
Molecular Weight
370.48
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Devereux, et al. Metabolism of prostaglandin PG-F2α by freshly isolated alveolar type II cells from lungs of adult male or pregnant rabbits. Prostaglandins Leukot. Med. 27, 43-52 (1987) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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