PGF2α-isopropyl ester

CAT: 0804-HY-106037-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-106037-01Size:1 mg
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Description
PGF2α-isopropyl ester is a Prostaglandin F2α (HY-12956) derivative, which is active in lowering the intraocular pressure (IOP) through increased uveoscleral outflow of aqueous humor. PGF2α-isopropyl ester causes side effects of conjunctival hyperemia and ocular irritation[1].
CAS Number
[53764-90-2]
UNSPSC
12352211
Hazard Statement
H225-H319-H336-H360
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/pgf2α-isopropyl-ester.html
Solubility
10 mM in DMSO
Smiles
CC(C)OC(CCC/C=C\C[C@@H]1[C@H]([C@@H](C[C@@H]1O)O)/C=C/[C@@H](O)CCCCC)=O
Molecular Formula
C23H40O5
Molecular Weight
396.56
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Stjernschantz JW. From PGF (2alpha) -isopropyl ester to latanoprost: a review of the development of xalatan: the Proctor Lecture. Invest Ophthalmol Vis Sci. 2001 May;42 (6) :1134-45.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

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