3β-Hydroxy-lup-20(29)-en-16-one

• UNSPSC Description:

  3β-Hydroxy-lup-20(29)-en-16-one (compound 9) is a dual inhibitor of AChE and BChE, with selectivity for BChE (IC50: 28.9 μM)[1].

• Target Antigen:

  Cholinesterase (ChE)

• Type:

  Reference compound

• Related Pathways:

  Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/3β-hydroxy-lup-20-29-en-16-one.html

• Solubility:

  10 mM in DMSO

• Smiles:

  C[C@]12[C@]3([C@@](CC[C@]1([H])[C@@]4([C@@](C(C)([C@H](CC4)O)C)([H])CC2)C)([H])[C@]5([H])[C@@](C(C3)=O)(CC[C@H]5C(C)=C)C)C

• Molecular Weight:

  440.70

• References & Citations:

  [1]Castro MJ, et al. Oxidation at C-16 enhances butyrylcholinesterase inhibition in lupane triterpenoids. Bioorg Chem. 2018 Sep;79:301-309.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  65043-60-9