Products for Research Use Only

Ataluren (Standard)

CAT: 0804-HY-14832R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14832R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Ataluren (Standard) is the analytical standard of Ataluren. This product is intended for research and analytical applications. Ataluren (PTC124) is an orally available CFTR-G542X nonsense allele inhibitor.
CAS Number
775304-57-9
Product Name Alternative
PTC124 (Standard)
UNSPSC
12352005
Target
Autophagy; CFTR; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/ataluren-standard.html
Purity
98.59
Smiles
O=C(C1=CC=CC(C2=NOC(C3=CC=CC=C3F)=N2)=C1)O
Molecular Formula
C15H9FN2O3
Molecular Weight
284.24
References & Citations
[1]Pettit RS, et al. CFTR Modulators for the Treatment of Cystic Fibrosis. P T. 2014 Jul;39 (7) :500-11.|[2]Welch EM, et al. PTC124 targets genetic disorders caused by nonsense mutations. Nature, 2007, 447 (7140), 87-91.|[3]Miller JN, et al. The novel Cln1 (R151X) mouse model of infantile neuronal ceroid lipofuscinosis (INCL) for testing nonsense suppression therapy. Hum Mol Genet. 2015 Jan 1;24 (1) :185-96.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards