Nortriptyline (Standard)

CAT: 0804-HY-118620R-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-118620R-01Size:5 mg
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Description
Nortriptyline (Standard) is the analytical standard of Nortriptyline. This product is intended for research and analytical applications. Nortriptyline (Desmethylamitriptyline), the main active metabolite of Amitriptyline, is a tricyclic antidepressant. Nortriptyline is a potent autophagy inhibitor and has anticancer effects[1][2][3]. N
CAS Number
[72-69-5]
Product Name Alternative
Desmethylamitriptyline (Standard) ; Desitriptilina (Standard)
UNSPSC
12352005
Target
Apoptosis; Autophagy; Drug Metabolite; Reference Standards
Type
Reference compound
Related Pathways
Apoptosis; Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/nortriptyline-standard.html
Smiles
CNCC/C=C1C2=CC=CC=C2CCC3=CC=CC=C\13
Molecular Formula
C19H21N
Molecular Weight
263.38
References & Citations
[1]Dean L. Amitriptyline Therapy and CYP2D6 and CYP2C19 Genotype. In: Pratt VM, Scott SA, Pirmohamed M, et al., eds. Medical Genetics Summaries. Bethesda (MD) : National Center for Biotechnology Information (US) ; March 23, 2017.|[2]Petrosyan E, et al. Repurposing Autophagy Regulators in Brain Tumors [published online ahead of print, 2022 Feb 18]. Int J Cancer. 2022;10.1002/ijc.33965. |[3]Sheau-Yun Yuan, et al. Nortriptyline induces mitochondria and death receptor-mediated apoptosis in bladder cancer cells and inhibits bladder tumor growth in vivo. Eur J Pharmacol. 2015 Aug 15:761:309-20.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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