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Recombinant Human Complement C1q subcomponent subunit C (C1QC), partial

CAT: 0399-CSB-EP003641HU1-03Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0399-CSB-EP003641HU1-03Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
C1QC
Abbreviation
Recombinant Human C1QC protein, partial
Gene Name
C1QC
UniProt
P02747
Expression Region
27-157aa
Organism
Homo sapiens (Human)
Target Sequence
QANTGCYGIPGMPGLPGAPGKDGYDGLPGPKGEPGIPAIPGIRGPKGQKGEPGLPGHPGKNGPMGPPGMPGVPGPMGIPGEPGEEGRYKQKFQSVFTVTRQTHQPPAPNSLIRFNAVLTNPQGDYDTSTGK
Tag
N-terminal 10xHis-GST-tagged and C-terminal Myc-tagged
Type
In Stock Protein
Source
E.coli
Field of Research
Immunology
Relevance
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca (2+) -dependent C1r (2) C1s (2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes
Endotoxin
Not test
Purity
Greater than 85% as determined by SDS-PAGE.
Activity
Not Test
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Molecular Weight
48.3 kDa
Storage Conditions
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Protein Length
Partial

UniProtKB · P02747

Complement C1q subcomponent subunit C

C1QC_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02747
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
C1QC
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q7Z502, Q96DL2, Q96H05
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Domain

CollagenRepeatSignal

Biological process

Complement pathwayImmunityInnate immunity

Disease

Disease variant

PTM

Disulfide bondGlycoproteinHydroxylation

Cellular component

Secreted

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