(RS)-MCPG

(RS)-MCPG

• CAS Number: 146669-29-6
• UNSPSC Description: (RS)-MCPG (alpha-MCPG) is a competitive and selective group I/group II metabotropic glutamate receptor (mGluR) antagonist. (RS)-MCPG blocks theta-burst stimulation (TBS)-induced shifts in both juvenile and neonatal rat hippocampal neurons[1][2].
• Target Antigen: mGluR
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Neuronal Signaling
• Applications: Neuroscience-Neuromodulation
• Field of Research: Neurological Disease
• Assay Protocol: https://www.medchemexpress.com/_RS_-MCPG.html
• Purity: 99.05
• Solubility: 1M NaOH : 100 mg/mL (ultrasonic;adjust pH to 10 with NaOH)|DMSO : 6 mg/mL (ultrasonic;warming)|H2O : < 0.1 mg/mL (ultrasonic;heat to 80°C)
• Smiles: CC(C(O)=O)(N)C1=CC=C(C(O)=O)C=C1
• Molecular Weight: 209.201
• References & Citations: [1]Yang B et al. Regulation of GABA Equilibrium Potential by mGluRs in Rat Hippocampal CA1 Neurons. PLoS One, 2015 Sep 21, 10(9):e0138215.|[2]Fiona Yeuk-Lun Choi, et al. The effects of (RS)-MCPG on amphetamine-induced sensitization in neonatal rats.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported