Human Eotaxin-3/CCL26 (Recombinant)

• Description:

  Human Eotaxin-3/CCL26_x000D_ Catalog number: B2010355_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Volume/Weight: 10 ug_x000D_ pH: 7.4 upon reconstitution_x000D_ Supplied as: Lyophilized Powder_x000D_ Appearance: Powder_x000D_ Applications: highly pure Human Eotaxin-3/CCL26 expressed in E. coli. This protein acts as a protein that signals exclusively via the CCR3 receptor and has eosinophil-selective chemoattractant activity._x000D_ Storage: -20C_x000D_ Keywords: rHuEotaxin-3/CCL26; C-C motif chemokine 26; MIP-4-alpha; TSC-1; SCYA26_x000D_ Grade: Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Fujimoto T, Imaeda H, Takahashi K, Nishida A, Shioya M, Inatomi O, Bamba S,_x000D_ Shiomi H, Tani M, Andoh A. Eotaxin-3 (CCL26) Expression in Human Pancreatic_x000D_ Myofibroblasts. Pancreas. 2016 Mar;45(3):420-4._x000D_ _x000D_ 2: Kohan M, Puxeddu I, Reich R, Levi-Schaffer F, Berkman N. Eotaxin-2/CCL24 and_x000D_ eotaxin-3/CCL26 exert differential profibrogenic effects on human lung_x000D_ fibroblasts. Ann Allergy Asthma Immunol. 2010 Jan;104(1):66-72._x000D_ _x000D_ 3: Stubbs VE, Power C, Patel KD. Regulation of eotaxin-3/CCL26 expression in_x000D_ human monocytic cells. Immunology. 2010 May;130(1):74-82._x000D_ PMC2855795._x000D_ _x000D_ 4: Banwell ME, Tolley NS, Williams TJ, Mitchell TJ. Regulation of human_x000D_ eotaxin-3/CCL26 expression: modulation by cytokines and glucocorticoids._x000D_ Cytokine. 2002 Mar 21;17(6):317-23._x000D_ _x000D_ 5: Miyagawa Y, Murakami A, Ebihara N. The proteolytic effect of mast cell_x000D_ tryptase to eotaxin-1/CCL11·eotaxin-2/CCL24 and eotaxin-3/CCL26 produced by_x000D_ conjunctival fibroblasts. Jpn J Ophthalmol. 2019 Mar;63(2):215-220._x000D_ _x000D_ 6: Petkovic V, Moghini C, Paoletti S, Uguccioni M, Gerber B. Eotaxin-3/CCL26 is_x000D_ a natural antagonist for CC chemokine receptors 1 and 5. A human chemokine with_x000D_ a regulatory role. J Biol Chem. 2004 May 28;279(22):23357-63._x000D_ _x000D_ 7: Rokudai A, Terui Y, Kuniyoshi R, Mishima Y, Mishima Y, Aizu-Yokota E, Sonoda_x000D_ Y, Kasahara T, Hatake K. Differential regulation of eotaxin-1/CCL11 and_x000D_ eotaxin-3/CCL26 production by the TNF-alpha and IL-4 stimulated human lung_x000D_ fibroblast. Biol Pharm Bull. 2006 Jun;29(6):1102-9._x000D_ _x000D_ 8: Blanchard C, Durual S, Estienne M, Emami S, Vasseur S, Cuber JC._x000D_ Eotaxin-3/CCL26 gene expression in intestinal epithelial cells is up-regulated_x000D_ by interleukin-4 and interleukin-13 via the signal transducer and activator of_x000D_ transcription 6. Int J Biochem Cell Biol. 2005 Dec;37(12):2559-73._x000D_ _x000D_ 9: Gela A, Kasetty G, Jovic S, Ekoff M, Nilsson G, Mörgelin M, Kjellström S,_x000D_ Pease JE, Schmidtchen A, Egesten A. Eotaxin-3 (CCL26) exerts innate host defense_x000D_ activities that are modulated by mast cell proteases. Allergy. 2015_x000D_ Feb;70(2):161-70._x000D_ 10: Min JY, Ocampo CJ, Stevens WW, Price CPE, Thompson CF, Homma T, Huang JH,_x000D_ Norton JE, Suh LA, Pothoven KL, Conley DB, Welch KC, Shintani-Smith S, Peters_x000D_ AT, Grammer LC 3rd, Harris KE, Hulse KE, Kato A, Modyanov NN, Kern RC, Schleimer_x000D_ RP, Tan BK. Proton pump inhibitors decrease eotaxin-3/CCL26 expression in_x000D_ patients with chronic rhinosinusitis with nasal polyps: Possible role of the_x000D_ nongastric H,K-ATPase. J Allergy Clin Immunol. 2017 Jan;139(1):130-141.e11. _x000D_ _x000D_ Products Related to Human Eotaxin-3/CCL26 : Proteins

• Short Description:

  Catalog Number: B2010355 (10 ug)_x000D_ Human Eotaxin-3/CCL26 is a high quality research product used as highly pure Human Eotaxin-3/CCL26 expressed in E. coli. This protein acts as a protein that signals exclusively via the CCR3 receptor and has eosinophil-selective chemoattractant activity. Custom bulk orders of this product are available upon request.

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3