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D-Cycloserine

CAT: 0804-HY-B0030-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B0030-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D-Cycloserine is an antibiotic which targets sequential bacterial cell wall peptidoglycan biosynthesis enzymes. D-Cycloserine is a partial NMDA agonist that can improve cognitive functions. D-Cycloserine can be used for multidrug-resistant tuberculosis research[1][2].
CAS Number
68-41-7
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antibiotic; Bacterial; iGluR
Type
Natural Products
Related Pathways
Anti-infection; Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Infection; Neurological Disease; Cancer
Assay Protocol
https://www.medchemexpress.com/D-Cycloserine.html
Purity
99.97
Solubility
DMSO : 1 mg/mL (warming) |H2O : 12.5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1[C@H](N)CON1
Molecular Formula
C3H6N2O2
Molecular Weight
102.09
Precautions
H302, H315, H319, H335
References & Citations
[1]Nitsche, M.A., et al., Consolidation of human motor cortical neuroplasticity by D-cycloserine. Neuropsychopharmacology, 2004. 29 (8) : p. 1573-8.|[2]Levin, E.D., et al., D-cycloserine selectively decreases nicotine self-administration in rats with low baseline levels of response. Pharmacol Biochem Behav, 2011. 98 (2) : p. 210-4.|[3]Sarah Batson, et al. Inhibition of D-Ala:D-Ala ligase through a phosphorylated form of the antibiotic D-cycloserine. Nat Commun. 2017 Dec 5;8 (1) :1939.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
Launched
Isoform
NMDA Receptor

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abx282593-01D (+) -Cycloserine

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