DAC 5945

• UNSPSC Description:

  DAC 5945 is a potent muscarinic antagonist in the airways than in the heart, with pKi values of 8.3 and 7.52 for M1 and M2, respectively[1][2].

• Target Antigen:

  mAChR

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Field of Research:

  Cardiovascular Disease

• Assay Protocol:

  https://www.medchemexpress.com/dac-5945.html

• Smiles:

  OC(C1=CC=CC=C1)(C2CCCCC2)CN3CCN(C=N)CC3.[H]Cl

• Molecular Weight:

  351.91

• References & Citations:

  [1]R E Howell, et al. Airway smooth muscle selectivity of the muscarinic antagonist DAC 5945 in vivo. Eur J Pharmacol. 1991 Apr 24;196(3):323-6.|[2]H N Doods, et al. Characterization of muscarinic receptors in guinea-pig uterus. Eur J Pharmacol. 1993 Dec 7;250(2):223-30.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  124065-13-0