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DAC 5945

CAT: 0804-HY-129709Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-129709Size:1 Each
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Description
DAC 5945 is a potent muscarinic antagonist in the airways than in the heart, with pKi values of 8.3 and 7.52 for M1 and M2, respectively[1][2].
CAS Number
124065-13-0
UNSPSC
12352005
Target
MAChR
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dac-5945.html
Smiles
OC(C1=CC=CC=C1)(C2CCCCC2)CN3CCN(C=N)CC3.[H]Cl
Molecular Formula
C19H30ClN3O
Molecular Weight
351.91
References & Citations
[1]R E Howell, et al. Airway smooth muscle selectivity of the muscarinic antagonist DAC 5945 in vivo. Eur J Pharmacol. 1991 Apr 24;196 (3) :323-6.|[2]H N Doods, et al. Characterization of muscarinic receptors in guinea-pig uterus. Eur J Pharmacol. 1993 Dec 7;250 (2) :223-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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