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Coumaran

CAT: 0804-HY-75247-01Size: 5 gDry Ice: NoHazardous: No
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CAT#:0804-HY-75247-01Size:5 g
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Coumaran (2,3-Dihydrobenzofuran) is an AChE inhibitor with antileishmanial activity. Coumaran may acquire antiparasitic capabilities through activation of macrophages and exert immunomodulatory activity. Coumaran can be used as a biopesticide.[2].
CAS Number
496-16-2
Product Name Alternative
2,3-Dihydrobenzofuran
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Cholinesterase (ChE) ; Endogenous Metabolite; Parasite
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Infection; Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/coumaran.html
Purity
99.67
Solubility
DMSO : 150 mg/mL (ultrasonic) |H2O : 150 mg/mL (ultrasonic)
Smiles
C12=CC=CC=C1CCO2
Molecular Formula
C8H8O
Molecular Weight
120.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Yallappa Rajashekar, et al. Acetylcholinesterase Inhibition by Biofumigant (Coumaran) From Leaves of Lantana Camara in Stored Grain and Household Insect Pests. Biomed Res Int. 2014;2014:187019.|[2]de Castro Oliveira LG, et al. In Vitro Effects of the Neolignan 2,3-Dihydrobenzofuran Against Leishmania Amazonensis. Basic Clin Pharmacol Toxicol. 2017 Jan;120 (1) :52-58.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
AChE

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