Coumarin 6

CAT: 0804-HY-N7131-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0804-HY-N7131-01Size:10 mg
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Description
Coumarin 6, a fluorescent dye, is used as a fluorescent probe in a microparticle drug delivery system to conduct in vivo tracking, cell uptake, and transport mechanism studies of drug delivery systems (λexc=450 nm, λem=505 nm) [1][2][3].
CAS Number
[38215-36-0]
UNSPSC
12171500
Hazard Statement
H315, H319
Target
Fluorescent Dye
Type
Dye Reagents
Related Pathways
Others
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/coumarin-6.html
Concentration
10mM
Purity
99.72
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C) |THF : 12.5 mg/mL (ultrasonic)
Smiles
O=C1C(C2=NC3=CC=CC=C3S2)=CC4=CC=C(N(CC)CC)C=C4O1
Molecular Formula
C20H18N2O2S
Molecular Weight
350.44
Precautions
H315, H319
References & Citations
[1]Purr E, et al. Preparation of PLGA Nanoparticles Encapsulated with Fluorescent Probe Coumarin-6[J]. bioRxiv, 2019: 614875.|[2]Rivolta I, et al. Cellular uptake of coumarin-6 as a model drug loaded in solid lipid nanoparticles. J Physiol Pharmacol. 2011 Feb;62 (1) :45-53. |[3]Miao X, et al. Transport Mechanism of Coumarin 6 Nanocrystals with Two Particle Sizes in MDCKII Monolayer and Larval Zebrafish. ACS Appl Mater Interfaces. 2016 May 25;8 (20) :12620-30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Dye Reagents
Clinical Information
No Development Reported

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