Scopolamine (hydrobromide trihydrate)

• UNSPSC Description:

  Scopolamine hydrobromide trihydrate (Hyoscine hydrobromide trihydrate) is used in ophthalmic preparations and has the potential for transdermal patches of motion sickness[1].

• Target Antigen:

  mAChR

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/scopolamine-hydrobromide-trihydrate.html

• Purity:

  99.89

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  O=C([C@@H](C1=CC=CC=C1)CO)O[C@H]2C[C@H]3[C@@H]4O[C@@H]4[C@H](N3C)C2.[H]Br.[H]O[H].[H]O[H].[H]O[H]

• Molecular Weight:

  438.31

• References & Citations:

  [1]National Toxicology Program. , et al. NTP Toxicology and Carcinogenesis Studies of Scopolamine Hydrobromide Trihydrate (CAS No. 6533-68-2) in F344 Rats and B6C3F1 Mice (Gavage Studies). Natl Toxicol Program Tech Rep Ser. 1997 Mar;445:1-277.Eur J Pharmacol. 2024 Aug 16:176903.|bioRxiv. 2023 Jul 6.|Eur J Med Chem. 2024 Dec 5.|Eur J Med Chem. 2023 Dec 21, 116071.|Food Chem. 30 November 2022, 133593.|J Neurosci. 2023 Jun 8;JN-RM-0128-23.|Neuropharmacology. 2022 Jul 11;109191.|Neurosci Lett. 2021 Sep 1;136209.|Phytomedicine. 2024 Jun 4:131:155802.|Phytomedicine. 2024 Mar 11, 155531.|Phytomedicine. 2024 Oct 31:135:156209.|Theranostics. 2024 Sep 3;14(14):5551-5570.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  6533-68-2