(±) -Scopolamine

• Description :

  (±) -Scopolamine (Atroscine) is the racemic modification of Scopolamine. (±) -Scopolamine inhibits α-adrenergic receptor activity. (±) -Scopolamine has Ki values of 33 μM and 7.25 nM for α1-adrenerg receptor and muscarinic cholinergic receptor, respectively[1].

• Product Name Alternative :

  Atroscine

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H312-H332

• Target :

  Adrenergic Receptor

• Type :

  Natural Products

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/minus-scopolamine.html

• Solubility :

  10 mM in DMSO

• Smiles :

  CN1[C@@H]2[C@H](O3)[C@H]3[C@H]1C[C@@H](OC(C(C4=CC=CC=C4)CO)=O)C2

• Molecular Formula :

  C17H21NO4

• Molecular Weight :

  303.35

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations :

  [1]Cantor EH, et al. Structure-activity requirements for hypotension and alpha-adrenergic receptor blockade by analogues of atropine. Eur J Pharmacol. 1983 May 20;90 (1) :75-83.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [138-12-5]