(±) -Scopolamine

• Description:

  (±) -Scopolamine (Atroscine) is the racemic modification of Scopolamine. (±) -Scopolamine inhibits α-adrenergic receptor activity. (±) -Scopolamine has Ki values of 33 μM and 7.25 nM for α1-adrenerg receptor and muscarinic cholinergic receptor, respectively[1].

• Product Name Alternative:

  Atroscine

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H312-H332

• Target:

  Adrenergic Receptor

• Type:

  Natural Products

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/minus-scopolamine.html

• Solubility:

  10 mM in DMSO

• Smiles:

  CN1[C@@H]2[C@H](O3)[C@H]3[C@H]1C[C@@H](OC(C(C4=CC=CC=C4)CO)=O)C2

• Molecular Formula:

  C17H21NO4

• Molecular Weight:

  303.35

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501

• References & Citations:

  [1]Cantor EH, et al. Structure-activity requirements for hypotension and alpha-adrenergic receptor blockade by analogues of atropine. Eur J Pharmacol. 1983 May 20;90 (1) :75-83.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Natural Products

• Clinical Information:

  No Development Reported

• CAS Number:

  138-12-5