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Recombinant Human CCL22 Protein

CAT: 0763-PDEH100737-01Size: 20 µgDry Ice: NoHazardous: No
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CAT#:0763-PDEH100737-01Size:20 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May play a role in the trafficking of activated/effector T-lymphocytes to inflammatory sites and other aspects of activated T-lymphocyte physiology. Chemotactic for monocytes, dendritic cells and natural killer cells. Mild chemoattractant for primary activated T-lymphocytes and a potent chemoattractant for chronically activated T-lymphocytes but has no chemoattractant activity for neutrophils, eosinophils, and resting T-lymphocytes. Binds to CCR4. Processed forms MDC (3-69), MDC (5-69) and MDC (7-69) seem not be active.
Abbreviation
CCL22
Synonyms
C-C motif chemokine 22; CC chemokine STCP-1; DC; MDC (1-69) ; Macrophage-derived chemokine; SCYA22; Small-inducible cytokine A22; Stimulated T-cell chemotactic protein 1
UniProt
O00626
Accession Number
O00626
Expression System
E.coli
Tag
N-His
Sequence
Gly25-Gln93
Field of Research
Immunology; Cardiovascular
Endotoxin
< 10 EU/mg of the protein as determined by the LAL method.
Purity
> 85% as determined by reducing SDS-PAGE.
Bioactivity
Not validated for activity
Reconstitution
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Shipping Conditions
This product is provided as lyophilized powder which is shipped with ice packs.
Storage Conditions
Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
Calculated Molecular Weight
10.4 kDa
Observed Molecular Weight
10 kDa
Species
Human

UniProtKB · O00626

C-C motif chemokine 22

CCL22_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
O00626
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CCL22
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
A0N0Q6, B2R4W2
Protein keywords

Biological process

Chemotaxis

Molecular function

Cytokine

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

Disulfide bond

Cellular component

Secreted

Domain

Signal
Product Datasheet
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