Recombinant Human CCL27 Protein

• Background:

  Human Chemokine (C-C Motif) Ligand 27 (CCL27) is a small cytokine that is a member of the CC chemokine family; it is expressed in numerous tissues, including gonads, thymus, placenta and skin. CCL27 elicits its chemotactic effects by binding to the chemokine receptor CCR10. Predominantly expressed in the skin, CCL27 is associated with T cell-mediated inflammation of the skin. Human and Mouse CCL27 share 84% sequence identity in the mature form.

• Abbreviation:

  CCL27

• Synonyms:

  C-C Motif Chemokine 27; CC Chemokine ILC; CCL27; CTACK; Cutaneous T-Cell-Attracting Chemokine; Eskine; IL-11 R-Alpha-Locus Chemokine; ILC; SCYA27; Skinkine; Small-Inducible Cytokine A27

• UniProt:

  Q9Y4X3

• Accession Number:

  Q9Y4X3

• Expression System:

  E.coli

• Tag:

  None

• Sequence:

  Phe25-Gly112

• Field of Research:

  Immunology

• Endotoxin:

  < 1.0 EU per μg of the protein as determined by the LAL method.

• Purity:

  > 95 % as determined by reducing SDS-PAGE.

• Bioactivity:

  Not validated for activity

• Reconstitution:

  Please refer to the printed manual for detailed information.

• Shipping Conditions:

  This product is provided as lyophilized powder which is shipped with ice packs.

• Storage Conditions:

  Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

• Calculated Molecular Weight:

  10.1 kDa

• Observed Molecular Weight:

  6-12 kDa

• Species:

  Human