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HS024 (TFA)

CAT: 0804-HY-P1215A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1215A-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HS024 is a selective MC4 receptor antagonist, with Kis of 0.29, 3.29, 5.45, 18.6 nM for MC4, MC5, MC3, and MC1, respectively. HS024 increase food intake[1].
UNSPSC
12352209
Target
Melanocortin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/hs024-tfa.html
Purity
99.80
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
CCCC[C@@H]1NC([C@@H](NC(C)=O)CSSC[C@@H](C(N)=O)NC(CNC([C@@H](NC([C@@H](NC([C@H](NC([C@@H](NC([C@@H](NC1=O)CCCNC(N)=N)=O)CC2=C[N]C=N2)=O)CC3=CC4=C(C=CC=C4)C=C3)=O)CCCNC(N)=N)=O)CC5C=NC6=C5C=CC=C6)=O)=O)=O.O=C(O)C(F)(F)F
Molecular Formula
C60H80F3N19O12S2
Molecular Weight
1380.52
References & Citations
[1]Kask A, et al. Discovery of a novel superpotent and selective melanocortin-4 receptor antagonist (HS024) : evaluation in vitro and in vivo. Endocrinology. 1998;139 (12) :5006-5014.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MC4R