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SPAA-52

CAT: 0804-HY-151591-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-151591-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SPAA-52 is an orally active, competitive and reversible low-molecular-weight protein tyrosine phosphatase (LMW-PTP) inhibitor (IC50=4 nM, Ki=1.2 nM) . SPAA-52 can be used in diabete research[1].
CAS Number
[2837000-75-4]
UNSPSC
12352005
Target
Phosphatase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/spaa-52.html
Purity
97.07
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=S(O)(NC(NC1=CC(Br)=C(C)C(Br)=C1)=O)=O
Molecular Formula
C8H8Br2N2O4S
Molecular Weight
388.03
References & Citations
[1]He R, et al. Structure-Based Design of Active-Site-Directed, Highly Potent, Selective, and Orally Bioavailable Low-Molecular-Weight Protein Tyrosine Phosphatase Inhibitors. J Med Chem. 2022 Oct 5.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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