Caspase-3-IN-1

• UNSPSC Description:

  Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1].

• Target Antigen:

  Caspase

• Type:

  Reference compound

• Related Pathways:

  Apoptosis

• Field of Research:

  Metabolic Disease; Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/caspase-3-in-1.html

• Smiles:

  O=S(C1=CC=C(C(C(C2=O)=O)=C1)N2CC3=CC=C(C=C3)OC)(N4[C@@H](CCC4)COC5=CN=CC=C5)=O

• Molecular Weight:

  507.56

• References & Citations:

  [1]Chu W, et al. N-benzylisatin sulfonamide analogues as potent caspase-3 inhibitors: synthesis, in vitro activity, and molecular modeling studies. J Med Chem. 2005 Dec 1;48(24):7637-47.

• Shipping Conditions:

  Room Temperature

• CAS Number:

  872254-32-5