AE-binding 1/Aebp1, Mouse (His-SUMO)

• UNSPSC Description:

  AE-binding protein 1/Aebp1 Protein, Mouse (His-SUMO) plays a critical role in regulating adipogenesis, and the proinflammation process in macrophages, including macrophage cholesterol homeostasis, foam cell formation and the development of atherosclerosis[1][2].

• Type:

  Recombinant Proteins

• Assay Protocol:

  https://www.medchemexpress.com/cytokines/ae-binding-protein-1-aebp1-protein-mouse-his-sumo.html

• Purity:

  90.0

• Smiles:

  QTVLTDDEIE EFLEGFLSEL ETQSPPREDD VEVQPLPEPT QRPRKSKAGG KQRADVEVPP EKNKDKEKKG KKDKGPKATK PLEGSTRPTK KPKEKPPKAT KKPKEKPPKA TKKPKEKPPK ATKKPKEKPP KATKRPSAGK KFSTVAPLET LDRLLPSPSN PSAQELPQKR DTPFPNAWQG QGEETQVEAK QPRPEPEEET EMPTLDYNDQ IEKEDYEDFE YIRRQKQPRP TPSRRRLWPE RPEEKTEEPE ERKEVEPPLK PLLPPDYGDS YVIPNYDDLD YYFPHPPPQK PDVGQEVDEE KEEMKKPKKE GSSPKEDTED KWTVEKNKDH KGPRKGEELE EEWAP

• Molecular Weight:

  Approximately 70 kDa.The reducing (R) protein migrat es as 70 kDa in SDS-PAGE may be due to relative charge.

• References & Citations:

  [1]Amin Majdalawieh, et al. Adipocyte enhancer-binding protein 1 is a potential novel atherogenic factor involved in macrophage cholesterol homeostasis and inflammation. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2346-51.|[2]Jun-Yan Liu, et al. AEBP1 promotes epithelial-mesenchymal transition of gastric cancer cells by activating the NF-κB pathway and predicts poor outcome of the patients. Sci Rep. 2018 Aug 10;8(1):11955.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Stored at -20°C for 2 years