Revaprazan (hydrochloride)

Chemical Information
Revaprazan Hydrochloride is the hydrochloride salt form of a lipophilic, weak base with potassium-competitive acid blocking (P-CAB) activity. Revaprazan concentrates highly in the gastric parietal cell canaliculus and on entering this acidic environment is instantly protonated and binds competitively and reversibly to the potassium binding site of the proton pump hydrogen-potassium adenosine triphosphatase (H+/K+ ATPase), thereby inhibiting the pump's activity and the parietal cell secretion of H+ ions into the gastric lumen, the final step in gastric acid production.
| CAS Number | 178307-42-1 |
| PubChem CID | 204103 |
| IUPAC Name | N-(4-fluorophenyl)-4,5-dimethyl-6-(1-methyl-3,4-dihydro-1H-isoquinolin-2-yl)pyrimidin-2-amine;hydrochloride |
| Molecular Formula | C22H24ClFN4 |
| Molecular Weight | 398.9 |
| Topological Polar Surface Area | 41.1 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 481 |
| Property | Value |
|---|---|
| Molecular Weight | 398.9 |
| Hydrogen Bond Donor Count | 2 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 3 |
| Exact Mass | 398.1673526 |
| Monoisotopic Mass | 398.1673526 |
| Topological Polar Surface Area | 41.1 Ų |
| Heavy Atom Count | 28 |
| Formal Charge | 0 |
| Complexity | 481 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 1 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| Covalently-Bonded Unit Count | 2 |
| Compound Is Canonicalized | Yes |
Related Products
Alternative Products
Popular Products

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (PE) discontinued
SKU: A0855-98-PE|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (AP) discontinued
SKU: A0855-98-AP|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2)
SKU: A0855-98|Size: 200 µL

ACVR2A
SKU: cyt-976-01|Size: 2µg

Plant Direct PCR Kit
SKU: PD105-00|Size: 10 Reactions

Anti-LRRK2/Dardarin Antibody
SKU: 56563|Size: 1 Each

MFNG Peptide
SKU: GTR19054825|Size: 100 µg

Anti-LRRK2/Dardarin Antibody (1D8)
SKU: MBS1571627-01|Size: 0.1 mg

Optiprep
SKU: 1893-01|Size: 250 mL

Carbonate-Bicarbonate Buffer Packs
SKU: 40220092-1|Size: 40 PKS

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2)
SKU: A0855-98|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (AP) discontinued
SKU: A0855-98-AP|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (APC) discontinued
SKU: A0855-98-APC|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (FITC) discontinued
SKU: A0855-98-FITC|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (HRP) discontinued
SKU: A0855-98-HRP|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (PE) discontinued
SKU: A0855-98-PE|Size: 200 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (MaxLight 405) discontinued
SKU: A0855-98-ML405|Size: 100 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (MaxLight 490) discontinued
SKU: A0855-98-ML490|Size: 100 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (MaxLight 550) discontinued
SKU: A0855-98-ML550|Size: 100 µL

ACVR2A, NT (Activin Receptor Type-2A, Activin Receptor Type IIA, ACTR-IIA, ACTRIIA, ACVR2) (MaxLight 650) discontinued
SKU: A0855-98-ML650|Size: 100 µL
