Citalopram (hydrobromide)
CAT:
804-HY-B1287-02
Size:
100 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Citalopram (hydrobromide)
- CAS Number: 59729-32-7
- UNSPSC Description: Citalopram hydrobromide is a selective serotonin reuptake inhibitor (SSRI). Citalopram hydrobromide inhibits 5-HT uptake into synaptosomes with an IC50 of 1.8 nM. Citalopram hydrobromideinhibits the 5-HT uptake in rabbit blood platelets with an IC50 of 14 nM. Antidepressant effect[1].
- Target Antigen: Autophagy; Serotonin Transporter
- Type: Reference compound
- Related Pathways: Autophagy;Neuronal Signaling
- Applications: Cancer-programmed cell death
- Field of Research: Neurological Disease; Cancer
- Assay Protocol: https://www.medchemexpress.com/Citalopram-hydrobromide.html
- Purity: 99.93
- Solubility: DMSO : ≥ 38 mg/mL|H2O : 10 mg/mL (ultrasonic)
- Smiles: N#CC1=CC2=C(C(C3=CC=C(F)C=C3)(CCCN(C)C)OC2)C=C1.[H]Br
- Molecular Weight: 405.30
- References & Citations: [1]J Hyttel. Citalopram--pharmacological profile of a specific serotonin uptake inhibitor with antidepressant activity. Prog Neuropsychopharmacol Biol Psychiatry. 1982;6(3):277-95.|[2]Laurent Sakka, et al. Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. Oncotarget. 2017 Jun 27;8(26):42789-42807.|[3]F Pollier, et al. Serotonin reuptake inhibition by citalopram in rat strains differing for their emotionality. Neuropsychopharmacology. 2000 Jan;22(1):64-76.Eur J Pharmacol. 2018 Sep 27;841:57-66.|J Clin Psychopharmacol. 2021 Jun 11.|Neurochem Int. 2019 Dec;131:104552.|Pharmacol Res Perspect. 2020 Apr;8(2):e00575.|Research Square Preprint. 2021 Feb.|Comput Struct Biotechnol J. 2023 Jul 7, 21, 3490-3502.|Orebro University. 2024.
- Shipping Conditions: Room Temperature
- Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
- Clinical Information: Launched