Citalopram

CAT: 0804-HY-121203-01Size: 50 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-121203-01Size:50 mg

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Description

Citalopram is a racemate mixture of the active S (+) -enantiomer (Escitalopram; HY-14258) and R (-) -enantiomer. Citalopram is an orally active selective serotonin reuptake inhibitor (SSRI). Citalopram is an antidepressant and enhances serotoninergic neurotransmission[1][2][3].

CAS Number

59729-33-8

UNSPSC

12352005

Hazard Statement

H302

Target

Serotonin Transporter

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease; Cancer

Assay Protocol

https://www.medchemexpress.com/citalopram.html

Purity

99.87

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

N#CC1=CC=C2C(CCCN(C)C)(OCC2=C1)C3=CC=C(C=C3)F

Molecular Formula

C20H21FN2O

Molecular Weight

324.40

Precautions

H302

References & Citations

[1]Carlsson B, et al. Enantioselective analysis of citalopram and escitalopram in postmortem blood together with genotyping for CYP2D6 and CYP2C19. J Anal Toxicol. 2009;33 (2) :65-76. |[2]Milne RJ, et al. Citalopram. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic potential in depressive illness. Drugs. 1991;41 (3) :450-477. |[3]Laurent Sakka, et al. Assessment of citalopram and escitalopram on neuroblastoma cell lines. Cell toxicity and gene modulation. Oncotarget. 2017 Jun 27;8 (26) :42789-42807.|[4]Zeng-Liang Jin, et al. Mouse strain differences in SSRI sensitivity correlate with serotonin transporter binding and function. Sci Rep. 2017 Aug 17;7 (1) :8631.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Comput Struct Biotechnol J. 2023 Jul 7:21:3490-3502.|Orebro University. 2024.|ACS Chem Neurosci. 2025 Jun 18;16 (12) :2312-2321.|Eur J Pharmacol. 2018 Dec 15:841:57-66.|J Clin Psychopharmacol. 2021 Sep-Oct;41 (5) :525-533.|Neurochem Int. 2019 Dec;131:104552.|Pharmacol Res Perspect. 2020 Apr;8 (2) :e00575.|Research Square Preprint. 2021 Feb.

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Citalopram

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