Azide-PEG5-Tos
CAT:
804-HY-140352-01
Size:
50 mg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Azide-PEG5-Tos
- CAS Number: 236754-49-7
- UNSPSC Description: Azide-PEG5-Tos is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1]. Azide-PEG5-Tos is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
- Target Antigen: ADC Linker
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/azide-peg5-tos.html
- Solubility: DMSO : ≥ 100 mg/mL
- Smiles: [N-]=[N+]=NCCOCCOCCOCCOCCOS(C1=CC=C(C)C=C1)(=O)=O
- Molecular Weight: 417.48
- References & Citations: [1]Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.
- Shipping Conditions: Room Temperature
- Clinical Information: No Development Reported