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6-Formylpterin

CAT: 0804-HY-113978-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-113978-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells[1].
CAS Number
712-30-1
Product Name Alternative
3,3',4,4'-Benzophenonetetracarboxylic acid, Pentacarboxybenzene
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Reactive Oxygen Species (ROS) ; Xanthine Oxidase
Type
Reference compound
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/6-formylpterin.html
Purity
98.0
Solubility
1 M NaOH : 5 mg/mL (ultrasonic; warming; heat to 60°C) |DMSO : < 1 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : 33.33 mg/mL (ultrasonic; adjust pH to 12 with 1 M NaOH)
Smiles
O=CC1=CN=C2N=C(N)NC(C2=N1)=O
Molecular Formula
C7H5N5O2
Molecular Weight
191.15
Precautions
H302, H315, H319, H335
References & Citations
[1]Arai T, et al. 6-formylpterin, a xanthine oxidase inhibitor, intracellularly generates reactive oxygen species involved in apoptosis and cell proliferation. Free Radic Biol Med. 2001 Feb 1;30 (3) :248-59.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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