Transglutaminase 2 Human Recombinant

• Description:

  Transglutaminase 2 Human Recombinant_x000D_ Catalog number: B2017405_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 100 µg_x000D_ Molecular Weight or Concentration: 79.4 kDa_x000D_ Supplied as: Solution_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -80°C_x000D_ Keywords: TG2, TGase 2, TGase C, TGase H, TGC, TGM2, Tissue Transglutaminase, Transglutaminase C, Transglutaminase H_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1: Shin S, Cho YP, Jun H, Park H, Hong HN, Kwon TW. Transglutaminase type 2 in human abdominal aortic aneurysm is a potential factor in the stabilization of extracellular matrix J Vasc Surg. 2013 May;57(5):1362-70._x000D_ 2: Eligini S, Fiorelli S, Tremoli E, Colli S. Inhibition of transglutaminase 2 reduces efferocytosis in human macrophages: Role of CD14 and SR-AI receptors Nutr Metab Cardiovasc Dis. 2016 Oct;26(10):922-30._x000D_ 3: Yi MC, Melkonian AV, Ousey JA, Khosla C. Endoplasmic reticulum-resident protein 57 (ERp57) oxidatively inactivates human transglutaminase 2 J Biol Chem. 2018 Feb 23;293(8):2640-2649._x000D_ 4: Maamra M, Benayad OM, Matthews D, Kettleborough C, Atkinson J, Cain K, Bon H, Brand H, Parkinson M, Watson PF, Johnson TS. Transglutaminase 2: Development of therapeutic antibodies reveals four inhibitory epitopes and confirms extracellular function in fibrotic remodelling Br J Pharmacol. 2022 Jun;179(11):2697-2712._x000D_ 5: Lai TS, Greenberg CS. Histaminylation of fibrinogen by tissue transglutaminase-2 (TGM-2): potential role in modulating inflammation Amino Acids. 2013 Oct;45(4):857-64._x000D_ 6: Király R, Csosz E, Kurtán T, Antus S, Szigeti K, Simon-Vecsei Z, Korponay-Szabó IR, Keresztessy Z, Fésüs L. Functional significance of five noncanonical Ca2+-binding sites of human transglutaminase 2 characterized by site-directed mutagenesis FEBS J. 2009 Dec;276(23):7083-96._x000D_ 7: Calikoglu Koyuncu AC, Nayman AH, Telci D, Torun Kose G. Tissue transglutaminase_variant 2-transduced mesenchymal stem cells and their chondrogenic potential Biotechnol Bioeng. 2020 Jun;117(6):1839-1852._x000D_ 8: Faye C, Inforzato A, Bignon M, Hartmann DJ, Muller L, Ballut L, Olsen BR, Day AJ, Ricard-Blum S. Transglutaminase-2: a new endostatin partner in the extracellular matrix of endothelial cells Biochem J. 2010 Apr 14;427(3):467-75._x000D_ 9: Cardoso I, Østerlund EC, Stamnaes J, Iversen R, Andersen JT, Jørgensen TJ, Sollid LM. Dissecting the interaction between transglutaminase 2 and fibronectin Amino Acids. 2017 Mar;49(3):489-500._x000D_ 10: Cho BR, Kim MK, Suh DH, Hahn JH, Lee BG, Choi YC, Kwon TJ, Kim SY, Kim DJ. Increased tissue transglutaminase expression in human atherosclerotic coronary arteries Coron Artery Dis. 2008 Nov;19(7):459-68. _x000D_ _x000D_ Products Related to Transglutaminase 2 Human Recombinant can be found at Proteins

• Short Description:

  Catalog Number: B2017405 (100 µg)_x000D_ Transglutaminase 2 (TG2) is an enzyme that plays a role in various biological processes, including cell adhesion, apoptosis, and tissue repair. It is involved in the crosslinking of proteins, which can affect the structure and function of tissues. This product has been used as a molecular tool for various biochemical applications. It has also been used in a wide array of other chemical and immunological applications. Custom bulk amounts of this product are available upon request._x000D_ _x000D_

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height :

  0.5

• CAS Number:

  9000-83-3