Guanabenz (Acetate)

• UNSPSC Description:

  Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

• Target Antigen:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Cardiovascular Disease; Endocrinology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/Guanabenz-Acetate.html

• Purity:

  98.77

• Solubility:

  DMSO : ≥ 51 mg/mL|H2O : 2.5 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.CC(O)=O

• Molecular Weight:

  291.13

• References & Citations:

  [1]Walker, B.R., L.E. Hare, and M.W. Deitch, Comparative antihypertensive effects of guanabenz and clonidine. J Int Med Res, 1982. 10(1): p. 6-14.|[2]Bonham, A.C., et al., Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine. J Hypertens Suppl, 1984. 2(3): p. S543-6.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  23256-50-0