Guanabenz (Acetate)

• Description :

  Guanabenz (Acetate) (BR-750) is an alpha-2 selective adrenergic agonist used as an antihypertensive agent.

• Product Name Alternative :

  BR-750; Wy8678 acetate

• UNSPSC :

  12352005

• Hazard Statement :

  H301

• Target :

  Adrenergic Receptor

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cardiovascular Disease; Endocrinology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Guanabenz-Acetate.html

• Concentration :

  10mM

• Purity :

  98.93

• Solubility :

  DMSO : ≥ 51 mg/mL|H2O : 2.5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  ClC1=C(/C=N/NC(N)=N)C(Cl)=CC=C1.CC(O)=O

• Molecular Formula :

  C10H12Cl2N4O2

• Molecular Weight :

  291.13

• Precautions :

  H301

• References & Citations :

  [1]Walker, B.R., L.E. Hare, and M.W. Deitch, Comparative antihypertensive effects of guanabenz and clonidine. J Int Med Res, 1982. 10 (1) : p. 6-14.|[2]Bonham, A.C., et al., Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine. J Hypertens Suppl, 1984. 2 (3) : p. S543-6.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, sealed storage, away from moisture)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [23256-50-0]