Taurodeoxycholate (sodium salt)

Taurodeoxycholate (sodium salt)

• CAS Number: 1180-95-6
• UNSPSC Description: Taurodeoxycholate sodium salt is a bile salt-related anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) inhibits various inflammatory responses[1] [2][3].
• Target Antigen: Endogenous Metabolite
• Type: Natural Products
• Related Pathways: Metabolic Enzyme/Protease
• Field of Research: Inflammation/Immunology
• Assay Protocol: https://www.medchemexpress.com/taurodeoxycholate-sodium-salt.html
• Purity: 99.80
• Solubility: DMSO : 100 mg/mL (ultrasonic)
• Smiles: C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C
• Molecular Weight: 521.69
• References & Citations: [1]Villavicencio-Queijeiro A, et al. The fully-active and structurally-stable form of the mitochondrial ATP synthase of Polytomella sp. is dimeric. J Bioenerg Biomembr. 2009 Feb;41(1):1-13.|[2]Kispal G,et al. Isolation and characterization of 3-hydroxyacyl coenzyme A dehydrogenase-binding protein from pig heart inner mitochondrial membrane. J Biol Chem. 1986 Oct 25;261(30):14209-13.|[3]Choi HJ, et al. Evaluation of acute and subacute toxicity of sodium taurodeoxycholate in rats. Drug Chem Toxicol. 2019 Jun 19:1-9.Research (Wash D C). 2022 Nov 2;2022:9784081.|SSRN. 2022 Jan 26.|Nature. 2024 Dec 18.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported