Sodium taurodeoxycholate hydrate (Standard)

• UNSPSC Description:

  Sodium taurodeoxycholate hydrate (Standard) is the analytical standard of Sodium taurodeoxycholate hydrate. This product is intended for research and analytical applications. Sodium taurodeoxycholate hydrate, a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Sodium taurodeoxycholate hydrate activates the S1PR2 pathway in addition to the TGR5 pathway[1].

• Target Antigen:

  Endogenous Metabolite; G protein-coupled Bile Acid Receptor 1

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein;Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Assay Protocol:

  https://www.medchemexpress.com/sodium-taurodeoxycholate-hydrate-standard.html

• Smiles:

  O=S([O-])(CCNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O)=O.[Na+].[x H2O]

• Molecular Weight:

  521.69

• References & Citations:

  [1]Chang S, et al. Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice. Front Immunol. 2018 Sep 18;9:1984.|[2]Yamaguchi J, et al. Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression. Surgery. 2004 Feb;135(2):215-21.

• Shipping Conditions:

  Room temperature

• CAS Number:

  207737-97-1