Sodium taurodeoxycholate hydrate

CAT:
804-HY-W089835-01
Size:
100 mg
  • Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
  • Dry Ice Shipment: No
Sodium taurodeoxycholate hydrate - image 1

Sodium taurodeoxycholate hydrate

  • UNSPSC Description:

    Sodium taurodeoxycholate hydrate, a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Sodium taurodeoxycholate hydrate activates the S1PR2 pathway in addition to the TGR5 pathway[1].
  • Target Antigen:

    Endogenous Metabolite; G protein-coupled Bile Acid Receptor 1
  • Type:

    Reference compound
  • Related Pathways:

    GPCR/G Protein;Metabolic Enzyme/Protease
  • Field of Research:

    Metabolic Disease
  • Assay Protocol:

    https://www.medchemexpress.com/sodium-taurodeoxycholate-hydrate.html
  • Purity:

    97.0
  • Solubility:

    DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 100 mg/mL (ultrasonic)
  • Smiles:

    O=S([O-])(CCNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O)=O.[Na+].[x H2O]
  • Molecular Weight:

    521.69
  • References & Citations:

    [1]Chang S, et al. Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice. Front Immunol. 2018 Sep 18;9:1984.|[2]Yamaguchi J, et al. Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression. Surgery. 2004 Feb;135(2):215-21.
  • Shipping Conditions:

    Room Temperature
  • Storage Conditions:

    4°C (Powder, sealed storage, away from moisture)
  • Clinical Information:

    No Development Reported
  • CAS Number:

    207737-97-1