Sodium taurodeoxycholate hydrate

Sodium taurodeoxycholate hydrate

• CAS Number: 207737-97-1
• UNSPSC Description: Sodium taurodeoxycholate hydrate, a bile acid, is an amphiphilic surfactant molecule synthesized from cholesterol in the liver. Sodium taurodeoxycholate hydrate activates the S1PR2 pathway in addition to the TGR5 pathway[1].
• Target Antigen: Endogenous Metabolite; G protein-coupled Bile Acid Receptor 1
• Type: Reference compound
• Related Pathways: GPCR/G Protein;Metabolic Enzyme/Protease
• Field of Research: Metabolic Disease
• Assay Protocol: https://www.medchemexpress.com/sodium-taurodeoxycholate-hydrate.html
• Purity: 97.0
• Solubility: DMSO : 100 mg/mL (ultrasonic;warming;heat to 60°C)|H2O : 100 mg/mL (ultrasonic)
• Smiles: O=S([O-])(CCNC(CC[C@@H](C)[C@H]1CC[C@@]2([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])C[C@H](O)[C@]12C)=O)=O.[Na+].[x H2O]
• Molecular Weight: 521.69
• References & Citations: [1]Chang S, et al. Taurodeoxycholate Increases the Number of Myeloid-Derived Suppressor Cells That Ameliorate Sepsis in Mice. Front Immunol. 2018 Sep 18;9:1984.|[2]Yamaguchi J, et al. Taurodeoxycholate increases intestinal epithelial cell proliferation through c-myc expression. Surgery. 2004 Feb;135(2):215-21.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, sealed storage, away from moisture)
• Clinical Information: No Development Reported