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Butenafine-d4

CAT: 0804-HY-114518S2Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-114518S2Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Butenafine-d4 (KP363-d4) is the deuterium labeled Butenafine. Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent[1]. Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as tinea pedis, tinea cruris, tinea versicolor[1][2].
CAS Number
1653964-70-5
Product Name Alternative
KP363-d4
UNSPSC
12352005
Target
Fungal; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; Others
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
CN(C([2H])([2H])C1=CC=C(C=C1)C(C)(C)C)C([2H])([2H])C2=C3C=CC=CC3=CC=C2
Molecular Formula
C23H23D4N
Molecular Weight
321.49
References & Citations
[1]Katrina Kokjohn, et al. Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria.Int J Dermatol. 2003 Sep;42 Suppl 1:11-7.|[2]Adriana Bezerra-Souza, et al. The antifungal compound butenafine eliminates promastigote and amastigote forms of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis. 2016 Dec;65 (6 Pt A) :702-707.|[3]Topical Antifungal Agent. Butenafine
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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