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Butenafine

CAT: 0804-HY-114518-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-114518-01Size:25 mg
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Description
Butenafine (KP363) is a potent and broad spectrum benzylamine antifungal agent[1]. Butenafine inhibits fungal ergosterol biosynthesis at the point of squalene epoxidation, leading to a deficiency of the fungal cell membranes. Butenafine is effective against dermatophytes infections, such as tinea pedis, tinea cruris, tinea versicolor[1][2].
CAS Number
101828-21-1
Product Name Alternative
KP363
UNSPSC
12352005
Hazard Statement
H302-H312-H315-H318-H335
Target
Fungal
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/butenafine.html
Purity
90.00
Solubility
10 mM in DMSO
Smiles
CN(CC1=CC=C(C=C1)C(C)(C)C)CC2=C3C=CC=CC3=CC=C2
Molecular Formula
C23H27N
Molecular Weight
317.47
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501
References & Citations
[1]Katrina Kokjohn, et al. Evaluation of in vitro activity of ciclopirox olamine, butenafine HCl and econazole nitrate against dermatophytes, yeasts and bacteria.Int J Dermatol. 2003 Sep;42 Suppl 1:11-7.|[2]Adriana Bezerra-Souza, et al. The antifungal compound butenafine eliminates promastigote and amastigote forms of Leishmania (Leishmania) amazonensis and Leishmania (Viannia) braziliensis. 2016 Dec;65 (6 Pt A) :702-707.|[3]Topical Antifungal Agent. Butenafine
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched

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