Recombinant Human B- and T-lymphocyte attenuator (BTLA) , partial (Active)
CAT:
399-CSB-MP773799HU-01
Size:
20 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
















Recombinant Human B- and T-lymphocyte attenuator (BTLA) , partial (Active)
Gene Name:
BTLAUniProt:
Q7Z6A9Expression Region:
31-150aaOrganism:
Homo sapiensTarget Sequence:
KESCDVQLYIKRQSEHSILAGDPFELECPVKYCANRPHVTWCKLNGTTCVKLEDRQTSWKEEKNISFFILHFEPVLPNDNGSYRCSANFQSNLIESHSTTLYVTDVKSASERPSKDEMASTag:
C-terminal hFc-Myc-taggedSource:
Mammalian cellField of Research:
CancerAssay Type:
Active Protein & In Stock ProteinRelevance:
Inhibitory receptor on lymphocytes that negatively regulates antigen receptor signaling via PTPN6/SHP-1 and PTPN11/SHP-2 (PubMed:12796776, PubMed:14652006, PubMed:15568026, PubMed:18193050). May interact in cis (on the same cell) or in trans (on other cells) with TNFRSF14 (PubMed:19915044). In cis interactions, appears to play an immune regulatory role inhibiting in trans interactions in naive T cells to maintain a resting state. In trans interactions, can predominate during adaptive immune response to provide survival signals to effector T cells (PubMed:19915044).Endotoxin:
Less than 1.0 EU/ug as determined by LAL method.Purity:
Greater than 90% as determined by SDS-PAGE.Activity:
YesBioactivity:
①Measured by its binding ability in a functional ELISA. Immobilized BTLA at 5 μg/ml can bind biotinylated human TNFRSF14 (CSB-MP842173HU-A), the EC50 is 137.8-233.4 ng/ml.Length:
PartialForm:
Lyophilized powderBuffer:
Lyophilized from a 0.2 μm filtered PBS, 6% Trehalose, pH 7.4Reconstitution:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Molecular Weight:
43.9 kDaStorage Conditions:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.Protein Length:
PartialCAS Number:
9000-83-3