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D-Allose

CAT: 0804-HY-128741-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-128741-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
D-Allose exhibits antitumor activity against various cancer cells. D-Allose scavenges reactive oxygen species (ROS) and reduces oxidative stress damage. D-Allose exhibits anti-inflammatory and neuroprotective through inhibition of TLR4/PI3K/AKT signaling pathway. D-Allose exhibits antihypertensive, cryoprotective, and anti-osteoporotic activities[1][2][5].
CAS Number
2595-97-3
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Akt; Apoptosis; Endogenous Metabolite; PI3K; Reactive Oxygen Species (ROS) ; Toll-like Receptor (TLR)
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Cancer; Inflammation/Immunology; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/d-allose.html
Purity
99.85
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C[C@@H]([C@@H]([C@@H]([C@@H](CO)O)O)O)O
Molecular Formula
C6H12O6
Molecular Weight
180.16
Precautions
H315, H319, H335
References & Citations
[1]Chen Z, et al., Recent research on the physiological functions, applications, and biotechnological production of D-allose. Appl Microbiol Biotechnol. 2018 May;102 (10) :4269-4278. |[2]Sui L, et al., Growth inhibitory effect of D-allose on human ovarian carcinoma cells in vitro. Anticancer Res. 2005 Jul-Aug;25 (4) :2639-44.|[3]Gao D, et al., Anti-inflammatory effect of D-allose in cerebral ischemia/reperfusion injury in rats. Neurol Med Chir (Tokyo) . 2013;53 (6) :365-74.|[4]Akumwami S, et al., Effects of D-Allose on experimental cardiac hypertrophy. J Pharmacol Sci. 2024 Oct;156 (2) :142-148.|[5]Luo Y, et al., D-allose Inhibits TLR4/PI3K/AKT Signaling to Attenuate Neuroinflammation and Neuronal Apoptosis by Inhibiting Gal-3 Following Ischemic Stroke. Biol Proced Online. 2023 Nov 28;25 (1) :30.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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