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α-conotoxin-MI

CAT: 0466-08CON012-00500Size: 0.5 mgDry Ice: NoHazardous: No
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CAT#:0466-08CON012-00500Size:0.5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
α-conotoxin MI (alpha-conotoxin MI) is a conotoxin that has been isolated from the venom of the cone snail Conus magus. α-conotoxin MI is a competitive antagonist of the muscle-type nicotinic acetylcholine receptors (nAChR) such as α-conotoxin GI or d-Turbocurarine. It binds to the receptor with a Kd value ~0,94nM. α-conotoxin MI allows to distinguish between the two agonist sites as it binds 10,000-fold more tightly to the α/δ than to the α/γ site.
CAS Number
83481-45-2
Specifications
α/δ site of the muscle-type nAChR blocker
Target
Acetylcholine receptors
Sequence
GRCCHPACGKNYSC
Peptide Number
08CON012
Disulfide Bonds
Cys3-Cys8; Cys4-Cys14
N Terminal Sequence
H
C Terminal Sequence
NH2

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