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NMB-1

CAT: 0466-NMB001-00100Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0466-NMB001-00100Size:0.1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
NMB-1 (Noxious mechanosensation blocker 1) is an analogue of a peptide isolated from a marine conesnail. This 19 amino acid peptide has shown a 30 fold selectivity in inhibiting slowly adapting mechanically activated currents over rapidly adapting ones. It is an interesting tool to distinguish between RA and SA currents. NMB-1 significantly blocks SA currents at 1 µM in sensory neurons contrary to GsMTx4. Some results suggest that NMB-1 could also block mechanosensitive ion channels in cochlear hair cells at 5 µM. Smartox Biotechnology is pleased to be the first company offering this research tool.
Specifications
SA currents blocker
Target
Mechanosensitive channels
Sequence
FNWRCCLIPCRRNHKKFFC
Peptide Number
NMB001
Disulfide Bonds
Cys5-Cys19; Cys6-Cys10
N Terminal Sequence
H
C Terminal Sequence
OH

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