2'-Azido-2'-deoxyuridine

2'-Azido-2'-deoxyuridine

• CAS Number: 26929-65-7
• UNSPSC Description: 2'-Azido-2'-deoxyuridine (N3dUrd) is a ribonucleotide reductase inhibitor. 2'-Azido-2'-deoxyuridine has anti-cancer activity[1]. 2'-Azido-2'-deoxyuridine is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
• Target Antigen: DNA/RNA Synthesis
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-azido-2-deoxyuridine.html
• Smiles: O=C(C=C1)NC(N1[C@@H]([C@H](N=[N+]=[N-])[C@@H]2O)O[C@@H]2CO)=O
• Molecular Weight: 269.21
• References & Citations: [1]Kang SH, et al. Biological activity and phosphorylation of 2_'-azido-2_'-deoxyuridine and 2_'-azido-2_'-deoxycytidine. Nucleosides Nucleotides. 1998 Jun;17(6):1077-88.
• Shipping Conditions: Room temperature