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C1s Enzyme

CAT: 0804-HY-E70390Size: 250 µgDry Ice: NoHazardous: No
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CAT#:0804-HY-E70390Size:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
C1s Enzyme is a subunit of the complement C1 complex, which activates the complement as a serine protease. C1s Enzyme cleaves LRP5 and LRP6, and thus activates the Wnt/β-Catenin signaling pathway. C1s Enzyme promotes the macrophage M2 polarization and inhibits M1 polarization. C1s Enzyme enhances efferocytosis, exhibits anti-inflammatory activity[1].
Product Name Alternative
Masp-2, c1 esterase, c1-esterase
UNSPSC
12352204
Target
Wnt
Type
Enzyme
Related Pathways
Stem Cell/Wnt
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/c1s-enzyme.html
Smiles
[C1sEnzyme]
References & Citations
[1]Yuan D, et al. Cytoprotective effects of C1s enzyme in macrophages in atherosclerosis mediated through the LRP5 and Wnt/β-catenin pathway. Mol Immunol. 2024 Feb;166:29-38.
Shipping Conditions
Room temperature
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Enzyme
Clinical Information
No Development Reported

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