Gemtuzumab ozogamicin (solution)
CAT:
804-HY-109539A
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Gemtuzumab ozogamicin (solution)
- CAS Number: 220578-59-6
- UNSPSC Description: Gemtuzumab ozogamicin (solution) is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML)[1][2].
- Target Antigen: Antibody-Drug Conjugates (ADCs); Apoptosis
- Type: ADC Related
- Related Pathways: Antibody-drug Conjugate/ADC Related;Apoptosis
- Applications: Cancer-programmed cell death
- Field of Research: Cancer
- Assay Protocol: https://www.medchemexpress.com/gemtuzumab-ozogamicin-solution.html
- Smiles: [Gemtuzumab ozogamicin (solution)]
- Molecular Weight: 151000 (average)
- References & Citations: [1]Yi Liu, et al. CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells. Int J Cancer. 2022 Apr 1;150(7):1141-1155.|[2]Baron J, et al. Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia. Expert Rev Clin Pharmacol. 2018;11(6):549-559.
- Shipping Conditions: Room temperature
- Clinical Information: No Development Reported