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Gemtuzumab ozogamicin (solution)

CAT: 0804-HY-109539ASize: InquireDry Ice: NoHazardous: No
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CAT#:0804-HY-109539ASize:Inquire
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
220578-59-6
UNSPSC Description
Gemtuzumab ozogamicin (solution) is an antibody-drug conjugate (ADC) consisting of a humanized immunoglobulin (IgG4) antibody directed against CD33 that is conjugated to the cytotoxic agent Calicheamicin (HY-19609). Calicheamicin is a cytotoxic antibiotic. Gemtuzumab ozogamicin can be used for the research of acute myeloid leukemia (AML)[1][2].
Target Antigen
Antibody-Drug Conjugates (ADCs); Apoptosis
Type
ADC Related
Related Pathways
Antibody-drug Conjugate/ADC Related;Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/gemtuzumab-ozogamicin-solution.html
Smiles
[Gemtuzumabozogamicin(solution)]
Molecular Weight
151000 (average)
References & Citations
[1]Yi Liu, et al. CD33-directed immunotherapy with third-generation chimeric antigen receptor T cells and gemtuzumab ozogamicin in intact and CD33-edited acute myeloid leukemia and hematopoietic stem and progenitor cells. Int J Cancer. 2022 Apr 1;150(7):1141-1155.|[2]Baron J, et al. Gemtuzumab ozogamicin for the treatment of acute myeloid leukemia. Expert Rev Clin Pharmacol. 2018;11(6):549-559.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported