TRPM4 rabbit pAb

• Background:

  The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. [provided by RefSeq, Mar 2016]

• Description:

  The protein encoded by this gene is a calcium-activated nonselective ion channel that mediates transport of monovalent cations across membranes, thereby depolarizing the membrane. The activity of the encoded protein increases with increasing intracellular calcium concentration, but this channel does not transport calcium. [provided by RefSeq, Mar 2016],

• Gene ID:

  54795

• UniProt:

  Q8TD43

• Cellular Locus:

  [Isoform 1]: Cell membrane ; Multi-pass membrane protein. Endoplasmic reticulum. Golgi apparatus.; [Isoform 2]: Cell membrane. Endoplasmic reticulum. Golgi apparatus.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from human TRPM4 AA range: 1089-1139

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB

• Validated Applications:

  WB

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1: 500-2000

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Subcellular Location:

  [Isoform 1]: Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum . Golgi apparatus .; [Isoform 2]: Cell membrane . Endoplasmic reticulum. Golgi apparatus.

• Gene ID (Human):

  54795

• SwissProt (Human):

  Q8TD43