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MCH (human, mouse, rat) (TFA)

CAT: 0804-HY-P1205A-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-P1205A-01Size:1 mg
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Description
MCH (human, mouse, rat) TFA is a potent peptide agonist of MCH-R and exhibits binding IC50 values of 0.3nM and 1.5 nM for MCH1R and MCH2R, respectively. MCH (human, mouse, rat) is a highly sensitive to MCH-2R in a CHO cell line and monitoring mobilization of intracellular calcium with FLIPR, exhibits functional activation EC50 values of 3.9 nM and 0.1nM for human MCH-1R and MCH-2R, respectively[1].
Product Name Alternative
Melanin-concentrating hormone (human, mouse, rat) (TFA)
UNSPSC
12352209
Target
MCHR1 (GPR24)
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mch-human-mouse-rat-tfa.html
Purity
99.09
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@H]1NC(C2([H])N(CCC2)C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(CNC([C@@H](NC([C@@H](NC([C@H](CSSC1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H](CCSC)NC([C@H](CC(O)=O)NC([C@@H](NC([C@@H](N)CC(O)=O)=O)CC3=CC=CC=C3)=O)=O)=O)=O)=O)=O)CCSC)=O)CC(C)C)=O)=O)CCCNC(N)=N)=O)C(C)C)=O)CC4=CC=C(C=C4)O)=O)CCCNC(N)=N)=O)=O)N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)C(C)C)=O)=O)CC5=CNC6=CC=CC=C56.OC(C(F)(F)F)=O
Molecular Formula
C107H161F3N30O28S4
Molecular Weight
2500.86
References & Citations
[1]A W Sailer, et al. Identification and characterization of a second melanin-concentrating hormone receptor, MCH-2R. Proc Natl Acad Sci U S A. 2001 Jun 19;98 (13) :7564-9.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported

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