DBCO-PEG6-NHS ester

• UNSPSC Description:

  DBCO-PEG6-NHS ester is a click chemistry PEG reagent containing an NHS ester that reacts specifically with primary amines, such as side chains of lysine residues or aminosilane-coated surfaces, under neutral or slightly alkaline conditions. , efficient reaction to form covalent bonds. DBCO-PEG6-NHS ester also contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups[1].

• Target Antigen:

  Biochemical Assay Reagents

• Type:

  Reference compound

• Related Pathways:

  Others

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/dbco-peg6-nhs-ester.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(N1C2=CC=CC=C2C#CC3=CC=CC=C3C1)CCC(NCCOCCOCCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O)=O

• Molecular Weight:

  737.79

• References & Citations:

  [1]Zimmerman ES, et al. Production of site-specific antibody-drug conjugates using optimized non-natural amino acids in a cell-free expression system. Bioconjug Chem. 2014 Feb 19;25(2):351-61.

• Shipping Conditions:

  Blue Ice

• Clinical Information:

  No Development Reported