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Isoetharine (mesylate)

CAT: 0804-HY-B1481-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-B1481-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isoetharine (Isoetarine) mesylate is an orally active selective agonist of β-adrenergic receptors. Isoetharine mesylate is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine mesylate can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].
CAS Number
7279-75-6
Product Name Alternative
Isoetarine (mesylate)
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isoetharine-mesylate.html
Purity
99.05
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CS(=O)(O)=O.OC1=CC(C(O)C(NC(C)C)CC)=CC=C1O
Molecular Formula
C14H25NO6S
Molecular Weight
335.42
Precautions
H302, H312, H332
References & Citations
[1]Katsuhisa Kurogi, et al. Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Biochem Pharmacol. 2012 Nov 1;84 (9) :1186-95.|[2]Monika Maciag, et al. Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish. Toxicol Appl Pharmacol. 2022 Jan 1;434:115812.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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