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Isoetharine

CAT: 0804-HY-B1481ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-B1481ASize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Isoetharine (Isoetarine) is an orally active selective agonist of β-adrenergic receptors. Isoetharine is a catechol-like agent and catechol O-methyltransferase (COMT) mediates its methylation. Isoetharine can promote the production of cAMP which stimulates the relaxation of smooth muscle cells and can be used as an emphysema, bronchitis and bronchodilator[1][2].
CAS Number
530-08-5
Product Name Alternative
Isoetarine
UNSPSC
12352005
Hazard Statement
H302-H312-H332
Target
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/isoetharine.html
Solubility
10 mM in DMSO
Smiles
OC1=CC=C(C(O)C(NC(C)C)CC)C=C1O
Molecular Formula
C13H21NO3
Molecular Weight
239.31
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P363-P501
References & Citations
[1]Katsuhisa Kurogi, et al. Concerted actions of the catechol O-methyltransferase and the cytosolic sulfotransferase SULT1A3 in the metabolism of catecholic drugs. Biochem Pharmacol. 2012 Nov 1;84 (9) :1186-95.|[2]Monika Maciag, et al. Evaluation of β-adrenergic ligands for development of pharmacological heart failure and transparency models in zebrafish. Toxicol Appl Pharmacol. 2022 Jan 1;434:115812.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
β adrenergic receptor

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