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(R) -Methotrexate-d3

CAT: 0804-HY-14519CS-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14519CS-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
(R) -Methotrexate-d3 is the deuterium labeled (R) -Methotrexate[1].
UNSPSC
12352005
Target
ADC Payload; Antifolate; Apoptosis; Bacterial; DNA/RNA Synthesis; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Antibody-drug Conjugate/ADC Related; Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Others
Field of Research
Others
Solubility
10 mM in DMSO
Smiles
O=C(O)CC[C@H](C(O)=O)NC(C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C([2H])([2H])[2H])C=C1)=O
Molecular Formula
C20H19D3N8O5
Molecular Weight
457.46
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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