VEGFR-2-IN-42

• UNSPSC Description:

  VEGFR-2-IN-42 (compound 8c) is a potent VEGFR-2 inhibitor. VEGFR-2-IN-42 shows anti-proliferative effect against MCF7 cells with the IC50 of 25 µM[1].

• Target Antigen:

  VEGFR

• Type:

  Reference compound

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Applications:

  Cancer-Kinase/protease

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/vegfr-2-in-42.html

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(NC1=CC=C(C)C=C1)NC2=NN=C(SC3=C4C=C([N+]([O-])=O)C=CC4=NC=N3)S2

• Molecular Weight:

  439.47

• References & Citations:

  [1]Masoudinia S, et al. Novel quinazolines bearing 1,3,4-thiadiazole-aryl urea derivative as anticancer agents: design, synthesis, molecular docking, DFT and bioactivity evaluations. BMC Chem. 2024;18(1):30. Published 2024 Feb 12.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported