Azido-PEG6-MS

CAT: 0804-HY-138363-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0804-HY-138363-01Size:5 mg
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Description
Azido-PEG6-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG6-MS is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
CAS Number
[352439-38-4]
UNSPSC
12352211
Hazard Statement
H302-H315-H319-H335
Target
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/azido-peg6-ms.html
Purity
95.32
Solubility
DMSO : ≥ 100 mg/mL
Smiles
[N-]=[N+]=NCCOCCOCCOCCOCCOCCOS(C)(=O)=O
Molecular Formula
C13H27N3O8S
Molecular Weight
385.43
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
PEG Linkers

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