XJB-5-131

CAT: 0804-HY-129460-01Size: 1 mgDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-129460-01Size:1 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

XJB-5-131 is a mitochondria-targeted ROS and electron scavenger[1]. XJB-5-131 is a bi-functional antioxidant that comprises a radical scavenger. XJB-5-131 is a synthetic antioxidant that targets mitochondria[2]. XJB-5-131 is an effective ionizing irradiation protector and mitigator of cord blood mononuclear cells (CB MNCs) [3].

CAS Number

866404-31-1

UNSPSC

12352005

Target

Reactive Oxygen Species (ROS)

Type

Reference compound

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/xjb-5-131.html

Purity

99.9

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

CC(C)(C)OC(N[C@@H](CC(C)C)/C=C/[C@H](CC1=CC=CC=C1)C(N2[C@@H](CCC2)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(OCC3=CC=CC=C3)=O)C(NC4CC(C)(N(O)C(C)(C4)C)C)=O)=O)=O)=O)=O

Molecular Formula

C53H81N7O9

Molecular Weight

960.25

References & Citations

[1]Carlos A Macias, et al. Treatment with a novel hemigramicidin-TEMPO conjugate prolongs survival in a rat model of lethal hemorrhagic shock. Ann Surg. 2007 Feb;245 (2) :305-14.|[2]Zhiyin Xun, et al. Targeting of XJB-5-131 to mitochondria suppresses oxidative DNA damage and motor decline in a mouse model of Huntington's disease. Cell Rep. 2012 Nov 29;2 (5) :1137-42.|[3]Julie P Goff, et al. Evaluation of potential ionizing irradiation protectors and mitigators using clonogenic survival of human umbilical cord blood hematopoietic progenitor cells. Exp Hematol. 2013 Nov;41 (11) :957-66.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-168559	EGFR-IN-131
HY-W247614-01	D 131
HY-122878	HS-131
HY-112279-01	GNE-131
HY-152249-01	Antibacterial agent 131
HY-149327	Anticancer agent 131
HY-D0660	Acid red 131
HY-173490	Antifungal agent 131
HY-162129	Antitumor agent-131
HY-P4031	HCV Peptide (131-140)

Alternative Products

Catalog	Name
JH920385	XJB-5-131
BA6999-1	GNE-131
524210	AMG-131
T69332-01	GD-131
255284	FC 131
T27048-01	CLR-131
MBS5764962	INT-131
MBS577844	DY-131
GTR19340033-01	D 131
7423/50	INT 131

XJB-5-131

Related Products

Alternative Products

Popular Products