Products for Research Use Only

Anti-Rem2 Antibody

CAT: 1303-75-286Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1303-75-286Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Rad And Gem-Like GTP-Binding Protein 2 or GTP-binding protein REM 2 is encoded by the gene Rem2 and is a member of the small GTPase superfamily and the Rad/Rem/Rem2/Gem/Kir (RGK) subfamily. REM2 binds GTP and plays roles in diverse processes including modulation of calcium channel currents, (Ref Zheng JQ et al. 2007), mediation of excitatory and inhibitory synapse development (Ref: Paradis et al. 2007) . REM2 is expressed in brain and kidney. Diseases associated with this gene include Long Qt Syndrome.
Description
Our Anti-Rem2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N324/2. It detects mouse and rat Rem2, and is purified by Protein A chromatography. It is great for use in IHC, ICC, WB.
Short Description
Our Anti-Rem2 mouse monoclonal primary antibody from NeuroMab is produced in-house from hybridoma clone N324/2. It detects mouse and rat Rem2, and is purified by protein a chromatography. It is great for use in WB, IHC, ICC, ELISA.
Synonyms
GTP-binding protein REM 2 (Rad and Gem-like GTP-binding protein 2)
Gene Name
Rem2
UniProt
Q9WTY2
Host
Mouse
Reactivity
Mouse and Rat
Immunogen
Fusion protein amino acids 1-341 (full-length) of rat Rem2 (accession number Q9WTY2)
Target
Rem2
Clonality
Monoclonal
Isotype
IgG1
Clone
N324/2
Type
Primary Antibody
Applications
WB, IHC, ICC, ELISA
Field of Research
Cell Signaling/G Protein Signaling
Concentration
1 mg/mL
Format
Purified by Protein A chromatography
Buffer
10 mM Tris, 50 mM Sodium Chloride, 0.065% Sodium Azide pH 7.125
Molecular Weight
45 kDa (and larger due to oligomerization)
Shipping Conditions
Shipped on ice packs
Storage Conditions
Aliquot and store at ≤ -20°C for long term storage. For short term storage, store at 2-8°C. For maximum recovery of product, centrifuge the vial prior to removing the cap.
Notes
Produced by in vitro bioreactor culture of hybridoma line followed by Protein A affinity chromatography. Purified mAbs are >90% specific antibody.
Specificity
Does not cross-react with Rad, Gem or Rem1
Quality Control
Each new lot of antibody is quality control tested by western blot on rat whole brain lysate and confirmed to stain the expected molecular weight band.
Recommended Usage
These antibodies are to be used as research laboratory reagents and are not for use as diagnostic or therapeutic reagents in humans.
Physical Properties
Liquid
Immunogen Species
Rat
WB Brain Quality Control
1
Conjugate
Unconjugated
RRID
AB_11001585